Hypoglycemia and Cardiovascular Risks

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Hypoglycemia and Cardiovascular Risks

A lthough hypoglycemia is the most common side effect of insulin therapy in diabetes and its morbidity is well known, for many years, the potentially life-threatening effects of hypoglycemia on the cardiovascular (CV) system have either been overlooked or have been dismissed as inconsequential to people with insulin-treated type 2 diabetes. This scenario may possibly be a consequence of the per...

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Hypoglycemia, Diabetes, and Cardiovascular Events

D iabetes is at epidemic proportions in the U.S. Patients with diabetes are at increased risk for microand macrovascular complications. The benefit of glycemic control in decreasing the risk for microvascular disease is well established. However, the role of glycemic control in decreasing macrovascular complications has been controversial. Several large clinical trials looking at this issue hav...

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Cardiovascular Importance of Hyperglycemia and Hypoglycemia

For addressing the question of cardiovascular importance of hypoglycemia, it is important to clarify its context. First, hypoglycemia is a result of treatment of hyperglycemia by oral insulin secretagogues or insulin. Chronic hyperglycemia usually expressed by HbA1c level is considered a risk factor for cardiovascular disease, although this epidemiological association does not necessarily mean ...

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Severe hypoglycemia and risks of vascular events and death.

BACKGROUND Severe hypoglycemia may increase the risk of a poor outcome in patients with type 2 diabetes assigned to an intensive glucose-lowering intervention. We analyzed data from a large study of intensive glucose lowering to explore the relationship between severe hypoglycemia and adverse clinical outcomes. METHODS We examined the associations between severe hypoglycemia and the risks of ...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2011

ISSN: 0149-5992,1935-5548

DOI: 10.2337/dc11-s220